The domain within your query sequence starts at position 2612 and ends at position 2679; the E-value for the RPT_3 domain shown below is 1.69e-7.

KVVKTGPSGHNIRSCPNLRGIPIGMLVLGNKVKAVGEVTNSEGAWVQLDKNSMVEFCESD
EGEAWSLA

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.