The domain within your query sequence starts at position 380 and ends at position 607; the E-value for the RPT_3 domain shown below is 1.77e-6.

TRKKLAQQLRDTTLLHRFWNLWQSRIEQREERVQTPSLHAALSHYRVTVLHKCVRVWLRY
VHKRQWQQLLRARADGHFQQRALPAAFYTWYRGWLWHQQRRILHTKAVRFHRGTLEKQVF
ALWRQKMSQHRENCLAERMAILQAEQQLLRRFWFVWHQQAAVCQLERQQQAMAIAHHHSG
LLRRAFCIWKESTQGFRIERMGRAQAAHFHSAQLLSRAWSMWRECLAL

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.