The domain within your query sequence starts at position 448 and ends at position 551; the E-value for the RPT_3 domain shown below is 1.3e-13.

GFPGQDGLAGPKGAPGERGPSGLTGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKV
GPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.