The domain within your query sequence starts at position 642 and ends at position 886; the E-value for the RPT_3 domain shown below is 1.52e-7.

NTSLGDMNCESHGPEVGFHADAQLEADQSPVNPEEVDLDLENQSVHSGISNLSFDSNASY
QSANDQPQGAWGEVNLDELNVDMEVKSNGCSSSELTFDSDSPLLSVTERSLLDFEGLNED
DFNLEDENCVSSSSDITFDSDIPDDSVADQPQVAVYEEEPVGLENKSNESCVSGITFDSD
IPLHSGNDHPEVAVKEVIIKEDENVHLEGKNDNPSGSEICLDSNVPLHSVTNSDVAVKKI
NPPKE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.