The domain within your query sequence starts at position 662 and ends at position 731; the E-value for the RPT_3 domain shown below is 1.96e-8.

GPAGEKGEPGSPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRG
PAGPKGEKGD

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.