The domain within your query sequence starts at position 1196 and ends at position 1249; the E-value for the RPT_4 domain shown below is 1.65e-5.

EEKRDLLKAHVQIPEEGPIGKVASLACEGEQQPDTRPEDLPGATPQTLPKDRQK

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.