The domain within your query sequence starts at position 146 and ends at position 233; the E-value for the RPT_4 domain shown below is 3.42e-6.

NLSLTLYEQVPEEFLKHQELNEFQNALKIFSKVKSGRVATTDVAAVLESMDISVNPEMIK
DVIQHAYEDNYHTMDIGDIIFTLDELQR

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.