The domain within your query sequence starts at position 289 and ends at position 345; the E-value for the RPT_5 domain shown below is 1.46e-9.

IKGEKGIPGFPGPRGEPGSHGPPGFPGFKGIQGAAGEPGLFGFLGPKGDLGDRGYPG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.