The domain within your query sequence starts at position 1287 and ends at position 1335; the E-value for the RPT_6 domain shown below is 7.63e-6.

GLKGDRGVPGERGLAGLPGQPGTPGHPGPPGEPGSDGAAGKEGPPGKQG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.