The domain within your query sequence starts at position 309 and ends at position 478; the E-value for the d1is2a1 domain shown below is 1e-28.

LQKACTIAVRYAVIRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYALHFMTTSLLQFF
HSSYSDILKRDFSLLPELHALSTGMKAMSSDFCAQGTEICRRACGGHGYSKLSGLPTLVT
QAIASCTYEGENTVLYLQVARFLMKSYLQAQVSPGSIPQKPLPQSVMYLA

This is a SCOP domain - please see the SCOP entry of d1is2a1 for further annotation