LysM

Lysin motif

• SMART accession number: SM00257
• Interpro abstract (IPR002482): This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation (PUBMED:1352512). This domain may have a general peptidoglycan binding function.
• GO process: cell wall catabolic process (GO:0016998)

There are 4369 LysM domains in 2890 proteins in SMART's nrdb database.

Metabolism (metabolic pathways involving proteins which contain this domain)

% proteins involved	KEGG pathway ID	Description
50.00	map00550	Peptidoglycan biosynthesis
27.85	map00530	Aminosugars metabolism
4.43	map00240	Pyrimidine metabolism
4.43	map00230	Purine metabolism
3.16	map00760	Nicotinate and nicotinamide metabolism
2.53	map00780	Biotin metabolism
2.53	map00310	Lysine degradation
2.53	map02010	ABC transporters - General
0.63	map00511	N-Glycan degradation
0.63	map00562	Inositol phosphate metabolism
0.63	map00632	Benzoate degradation via CoA ligation
0.63	map01032	Glycan structures - degradation

This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with LysM domain which could be assigned to a KEGG orthologous group, and not all proteins containing LysM domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.

Structure (3D structures containing this domain)

3D Structures of LysM domains in PDB

PDB code	Title
1e0g	Lysm domain from e.coli mltd
1y7m	Crystal structure of the b. subtilis ykud protein at 2 a resolution
2djp	The solution structure of the lysm domain of human hypothetical protein sb145

Links (links to other resources describing this domain)

• INTERPRO: IPR002482