• Links (links to other resources describing this domain)
  • AT_hook

    DNA binding domain with preference for A/T rich regions
    AT_hook
    SMART accession number:SM00384
    Description: Small DNA-binding motif first described in the high mobility group non-histone chromosomal protein HMG-I(Y).
    Interpro abstract (IPR017956):

    AT hooks are DNA-binding motifs with a preference for A/T rich regions. These motifs are found in a variety of proteins, including the high mobility group (HMG) proteins [(PUBMED:11406267)], in DNA-binding proteins from plants [(PUBMED:8790293)] and in hBRG1 protein, a central ATPase of the human switching/sucrose non-fermenting (SWI/SNF) remodeling complex [(PUBMED:17081121)].

    GO function:DNA binding (GO:0003677)
    Family alignment:
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    There are 20276 AT_hook domains in 10831 proteins in SMART's nrdb database.

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