BASIC

Basic domain in HLH proteins of MYOD family
BASIC
SMART accession number:SM00520
Description: -
Interpro abstract (IPR002546):

Members of the bHLH family of transcription factors share homology within a basic domain and an adjacent helix-loop-helix motif. Myogenic factor MyoD belongs to the bHLH family [ (PUBMED:8790335) ].

This domain can be found at the N terminus of MyoD, which is muscle specific protein that control muscle development. This domain includes the predicted N-terminal transcription activation domain and part of the basic domain [ (PUBMED:9343420) (PUBMED:17395511) ].

Family alignment:
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There are 1406 BASIC domains in 1399 proteins in SMART's nrdb database.

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