LEMin nuclear membrane-associated proteins
|SMART accession number:||SM00540|
|Description:||LEM, domain in nuclear membrane-associated proteins, including lamino-associated polypeptide 2 and emerin.|
|Interpro abstract (IPR003887):|
The LEM domain is found in nuclear membrane-associated proteins, including lamino-associated polypeptide 2 and emerin [(PUBMED:11792821)]. Defects in the emerin gene are a cause of Emery-Dreifuss muscular dystrophy, an X-linked disorder characterised by early contractures, muscle wasting, weakness and cardiomyopathy.
|GO component:||nuclear envelope (GO:0005635)|
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