PlsCPhosphate acyltransferases |
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| SMART accession number: | SM00563 |
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| Description: | Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family. |
| Interpro abstract (IPR002123): | This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function (PUBMED:9259571). This family also includes tafazzin subfamily (Q16635) (PUBMED:8630491). |
| GO process: | metabolic process (GO:0008152) |
| GO function: | acyltransferase activity (GO:0008415) |
| Family alignment: |
There are 3789 PlsC domains in 3788 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
- Literature (relevant references for this domain)
- Disease (disease genes where sequence variants are found in this domain)
- Metabolism (metabolic pathways involving proteins which contain this domain)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)

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