CADG

Dystroglycan-type cadherin-like domains.
CADG
SMART accession number:SM00736
Description: Cadherin-homologous domains present in metazoan dystroglycans and alpha/epsilon sarcoglycans, yeast Axl2p and in a very large protein from magnetotactic bacteria. Likely to bind calcium ions.
Interpro abstract (IPR006644):

In animals, cadherin domain-containing proteins are adhesion molecules that modulate a wide variety of processes including cell polarization and migration but they have also been identified in yeast and magnetotactic bacteria. Crystal structures have revealed that multiple cadherin domains form Ca 2+ -dependent rod-like structures with a conserved Ca 2+ -binding pocket at the domain-domain interface [ (PUBMED:11909544) ].

GO component:membrane (GO:0016020)
Family alignment:
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There are 15915 CADG domains in 6264 proteins in SMART's nrdb database.

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