IMP dehydrogenase / GMP reductase domain
SMART accession number:SM01240
Description: This family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure. In the inosine monophosphate dehydrogenases 2 CBS domains are inserted in the TIM barrel (PMID: 10200156). This family is a member of the common phosphate binding site TIM barrel family.
Family alignment:
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There are 30692 IMPDH domains in 30689 proteins in SMART's nrdb database.

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