The domain within your query sequence starts at position 358 and ends at position 482; the E-value for the SPRY domain shown below is 2.94e-26.

TGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPH
VHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFN
FGARP

SPRY

Domain in SPla and the RYanodine Receptor.
SPRY
SMART accession number:SM00449
Description: Domain of unknown function. Distant homologues are domains in butyrophilin/marenostrin/pyrin homologues.
Interpro abstract (IPR003877):

The SPRY domain is named from SPla and the RYanodine Receptor. Its function is unknown. Distant homologues are domains in butyrophilin/marenostrin/pyrin [ (PUBMED:9204703) ]. Ca 2+ -release from the sarcoplasmic or endoplasmic reticulum, the intracellular Ca 2+ store, is mediated by the ryanodine receptor (RyR) and/or the inositol trisphosphate receptor (IP3R).

GO function:protein binding (GO:0005515)
Family alignment:
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There are 24471 SPRY domains in 20651 proteins in SMART's nrdb database.

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