 Sec63Sec63 Brl domain | |
|---|---|
| SMART ACC: | SM000973 |
| Description: | This domain was named after the yeast Sec63 (or NPL1) (also known as the Brl domain) protein in which it was found. This protein is required for assembly of functional endoplasmic reticulum translocons (PUBMED:16368690), (PUBMED:11023840). Other yeast proteins containing this domain include pre-mRNA splicing helicase BRR2, HFM1 protein and putative helicases. |
| InterPro ACC: | IPR004179 |
| InterPro abstract: | This domain was named after the yeast Sec63 (or NPL1) (also known as the Brl domain) protein in which it was found. This protein is required for assembly of functional endoplasmic reticulum translocons [ PUBMED:16368690 PUBMED:11023840 ]. Other … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 9 838 Sec63 domains in 6 927 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing Sec63 domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Sec63 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Sec63 domain which could be assigned to a KEGG orthologous group, and not all proteins containing Sec63 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.