Zds_C

Activator of mitotic machinery Cdc14 phosphatase activation C-term
Zds_C
SMART accession number:SM01327
Description: This region of the Zds1 protein is critical for sporulation and has also been shown to suppress the calcium sensitivity of Zds1 deletions (PMID:16322512). The C-terminal motif is common to both Zds1 and Zds2 proteins, both of which are putative interactors of Cdc55 and are required for the completion of mitotic exit and cytokinesis. They both contribute to timely Cdc14 activation during mitotic exit and are required downstream of separase to facilitate nucleolar Cdc14 (PMID:18762578).
Family alignment:
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There are 185 Zds_C domains in 185 proteins in SMART's nrdb database.

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