Domains within Arthrobacter sp. FB24 protein A0JV53_ARTS2 (A0JV53)

Signal transduction histidine kinase regulating citrate/malate metabolism

Alternative representations: 1 /

Protein length543 aa
Source databaseUniProt
Identifiers A0JV53_ARTS2, A0JV53

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

A0JV53_ARTS2 is shown as Arth_1529 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Arth_1529

Protein A0JV53_ARTS2 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system

KEGG orthologous groups

KONameDescription
K02476K02476two-component system, CitB family, sensor kinase [EC:2.7.13.3]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 290399.Arth_1529 in eggNOG.

OGTaxonomic classDescription
LCOG3290All organisms (root)two-component system, CitB family, sensor kinase [EC:2.7.13.3],two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3],two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
COG3290Bacteria (superkingdom)two-component system, CitB family, sensor kinase [EC:2.7.13.3],two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3],two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
68B3QActinobacteria (phylum)two-component system, CitB family, sensor kinase [EC:2.7.13.3]
FBBR9Actinomycetia (class)two-component system, CitB family, sensor kinase [EC:2.7.13.3]
EVVENMicrococcales (order)two-component system, CitB family, sensor kinase [EC:2.7.13.3]
8208TMicrococcaceae (family)two-component system, CitB family, sensor kinase [EC:2.7.13.3]
B6NGKArthrobacter (genus)two-component system, CitB family, sensor kinase [EC:2.7.13.3]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: