Domains within Arthrobacter sp. FB24 protein A0K0P6_ARTS2 (A0K0P6)

Putative signal transduction histidine kinase

Alternative representations: 1 /

Protein length624 aa
Source databaseUniProt
Identifiers A0K0P6_ARTS2, A0K0P6

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

A0K0P6_ARTS2 is shown as Arth_3491 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Arth_3491

Protein A0K0P6_ARTS2 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system

KEGG orthologous groups

KONameDescription
K07778desKtwo-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
K07675uhpBtwo-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 290399.Arth_3491 in eggNOG.

OGTaxonomic classDescription
LCOG4585All organisms (root)two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3],two-component system, NarL family, sensor kinase [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
COG4585Bacteria (superkingdom)two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3],two-component system, NarL family, sensor kinase [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
69SSHActinobacteria (phylum)two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3],two-component system, NarL family, sensor kinase [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
FA5Z7Actinomycetia (class)two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3],two-component system, NarL family, sensor kinase [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3]
EW07AMicrococcales (order)two-component system, NarL family, sensor kinase [EC:2.7.13.3]
81ZJUMicrococcaceae (family)HisKA_3,HATPase_c
B6NGBArthrobacter (genus)HisKA_3,HATPase_c

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: