Domains within Acidothermus cellulolyticus 11B protein A0LWR1_ACIC1 (A0LWR1)

Response regulator receiver modulated diguanylate phosphodiesterase

Alternative representations: 1 /

Protein length402 aa
Source databaseUniProt
Identifiers A0LWR1_ACIC1, A0LWR1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

A0LWR1_ACIC1 is shown as Acel_2099 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Acel_2099

Protein A0LWR1_ACIC1 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system
map02025Biofilm formation - Pseudomonas aeruginosa

KEGG orthologous groups

KONameDescription
K02488pleDtwo-component system, cell cycle response regulator [EC:2.7.7.65]
K21023mucRdiguanylate cyclase [EC:2.7.7.65]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 351607.Acel_2099 in eggNOG.

OGTaxonomic classDescription
LCOG2200All organisms (root)diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],RNase E specificity factor CsrD
LCOG3706All organisms (root)two-component system, cell cycle response regulator [EC:2.7.7.65],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],diguanylate cyclase [EC:2.7.7.65]
COG2200Bacteria (superkingdom)diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],RNase E specificity factor CsrD
COG3706Bacteria (superkingdom)two-component system, cell cycle response regulator [EC:2.7.7.65],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],diguanylate cyclase [EC:2.7.7.65]
69BX4Actinobacteria (phylum)EAL,GAF_2,PAS_3
FC1PNActinomycetia (class)EAL,GAF_2,Response_reg

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: