Domains within Clostridium novyi NT protein A0Q276_CLONN (A0Q276)
Sensory transduction histidine kinase
Alternative representations: 1 /
| Protein length | 1666 aa |
|---|---|
| Source database | UniProt |
| Identifiers | A0A072WXC9_CLOBO, A0A072WXC9, A0A072X287_CLOBO, A0A072X287, A0Q276_CLONN, A0Q276 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
This domain architecture was probably invented with the emergence of cellular organisms
Predicted functional partners
A0Q276_CLONN is shown as 
ABK61427.1 in the network
Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.
The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein A0Q276_CLONN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map02020 | Two-component system | |
| map05152 | Tuberculosis | |
| map02025 | Biofilm formation - Pseudomonas aeruginosa |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K02484 | K02484 | two-component system, OmpR family, sensor kinase [EC:2.7.13.3] | |
| K12132 | prkC, stkP | eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] | |
| K11527 | K11527 | two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] | |
| K01768 | E4.6.1.1 | adenylate cyclase [EC:4.6.1.1] | |
| K03413 | cheY | two-component system, chemotaxis family, chemotaxis protein CheY |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 386415.NT01CX_0224 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG0642 | All organisms (root) | two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| LCOG2203 | All organisms (root) | adenylate cyclase [EC:4.6.1.1],two-component system, NtrC family, sensor kinase [EC:2.7.13.3],diguanylate cyclase [EC:2.7.7.65] |
| LCOG0515 | All organisms (root) | eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],serine/threonine protein kinase, bacterial [EC:2.7.11.1],serine/threonine-protein kinase PknG [EC:2.7.11.1] |
| LCOG0784 | All organisms (root) | two-component system, chemotaxis family, chemotaxis protein CheY,two-component system, chemotaxis family, chemotaxis protein CheV,two-component system, sensor histidine kinase [EC:2.7.13.3] |
| LCOG3899 | All organisms (root) | eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],adenylate cyclase [EC:4.6.1.1],two-component system, NtrC family, sensor kinase [EC:2.7.13.3] |
| COG2203 | Bacteria (superkingdom) | adenylate cyclase [EC:4.6.1.1],two-component system, NtrC family, sensor kinase [EC:2.7.13.3],diguanylate cyclase [EC:2.7.7.65] |
| COG3899 | Bacteria (superkingdom) | eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],adenylate cyclase [EC:4.6.1.1],two-component system, NtrC family, sensor kinase [EC:2.7.13.3] |
| COG0784 | Bacteria (superkingdom) | two-component system, chemotaxis family, chemotaxis protein CheY,two-component system, chemotaxis family, chemotaxis protein CheV,two-component system, sensor histidine kinase [EC:2.7.13.3] |
| COG0642 | Bacteria (superkingdom) | two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| COG0515 | Bacteria (superkingdom) | eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],serine/threonine protein kinase, bacterial [EC:2.7.11.1],serine/threonine-protein kinase PknG [EC:2.7.11.1] |
| 9XB7G | Firmicutes (phylum) | two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3],two-component system, sensor histidine kinase ChiS |
| 992FJ | Clostridia (class) | two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3],two-component system, sensor histidine kinase ChiS |
| 7VPMN | Eubacteriales (order) | two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3],two-component system, sensor histidine kinase ChiS |
| ECASP | Clostridiaceae (family) | two-component system, sensor histidine kinase ChiS |
| FHT0P | Clostridium (genus) | two-component system, sensor histidine kinase ChiS |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.