Domains within Mycobacterium smegmatis str. MC2 155 protein I7G226_MYCS2 (I7G226)

GntR family transcriptional regulator

Alternative representations: 1 /

Protein length228 aa
Source databaseUniProt
Identifiers A0QQ19_MYCS2, A0QQ19, A0A0D6GDM2_MYCSM, A0A0D6GDM2, I7G226_MYCS2, I7G226

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

I7G226_MYCS2 is shown as ABK74264.1 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ABK74264.1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 246196.MSMEG_0596 in eggNOG.

OGTaxonomic classDescription
LCOG2186All organisms (root)GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex,GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA,GntR family transcriptional regulator, uxu operon transcriptional repressor
COG2186Bacteria (superkingdom)GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex,GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA,GntR family transcriptional regulator, uxu operon transcriptional repressor
6AR8QActinobacteria (phylum)GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex,GntR family transcriptional regulator, galactonate operon transcriptional repressor,GntR family transcriptional regulator, sialic acid-inducible nan operon repressor
FAJZFActinomycetia (class)GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex,GntR family transcriptional regulator, galactonate operon transcriptional repressor,GntR family transcriptional regulator, sialic acid-inducible nan operon repressor
EN7YECorynebacteriales (order)GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex,GntR family transcriptional regulator, sialic acid-inducible nan operon repressor,GntR family transcriptional regulator, galactonate operon transcriptional repressor
58C1GMycobacteriaceae (family)GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex
DY8KZMycolicibacterium (genus)GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: