Domains within Aspergillus fumigatus Af293 protein H2B_ASPFU (Q4WWC5)

Histone H2B

Alternative representations: 1 /

Protein length140 aa
Source databaseUniProt
Identifiers H2B_NEOFI, A1D8G9, A0A0K8LCQ9_9EURO, A0A0K8LCQ9, A0A1L9RH95_ASPWE, A0A1L9RH95, A0A229XRR1_ASPFM, A0A229XRR1, B0XZ99_ASPFC, B0XZ99, A0A0S7DR56_9EURO, A0A0S7DR56, A0A2I1C1P6_9EURO, A0A2I1C1P6, H2B_ASPFU, Q4WWC5

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

H2B_ASPFU is shown as htb1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for htb1

Protein H2B_ASPFU is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05203Viral carcinogenesis
map05034Alcoholism

KEGG orthologous groups

KONameDescription
K11252H2Bhistone H2B

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 330879.Q4WWC5 in eggNOG.

OGTaxonomic classDescription
7553EAll organisms (root)histone H2B,histone H1/5,histone H4
FTHCGDikarya (subkingdom)histone H2B
KOG1744Eukaryota (superkingdom)histone H2B,histone H1/5,histone H4
BKHN8Fungi (kingdom)histone H2B
9SEUFAscomycota (phylum)histone H2B
C2KUAPezizomycotina (subphylum)histone H2B
CGH2HEurotiomycetes (class)histone H2B
7BI4UEurotiomycetidae (subclass)histone H2B
CJZFCEurotiales (order)histone H2B
7KFBJOpisthokonta (clade)histone H2B,histone H1/5,histone H4
CW0NIAspergillaceae (family)histone H2B
AQV2MAspergillus (genus)histone H2B

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: