Domains within Mycobacterium bovis AF2122/97 protein MPRA_MYCBO (Q7U0X4)

Response regulator MprA

Alternative representations: 1 /

Protein length230 aa
Source databaseUniProt
Identifiers A0A1R3XX06, Q84BX0, X2BGG7, MPRA_MYCBP, A1KHB7, A0A109S6T8_MYCBI, A0A109S6T8, A0A0C7DNT3_MYCBI, A0A0C7DNT3, A0A109SV09_9MYCO, A0A109SV09, A0A109SLW1_9MYCO, A0A109SLW1, F8M4M7_MYCA0, F8M4M7, G0TG93_MYCCP, G0TG93, A0A0T9ES79_MYCTX, A0A0T9ES79, A0A0U0U9K9_MYCTX, A0A0U0U9K9, A0A0T9BUP3_MYCTX, A0A0T9BUP3, MPRA_MYCBO, Q7U0X4

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

MPRA_MYCBO is shown as RN08_1094 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RN08_1094

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 1765.Mb1595_p1102 in eggNOG.

OGTaxonomic classDescription
GJXS0Mycobacterium tuberculosis complex (species group)two-component system, OmpR family, response regulator MprA
LCOG0745All organisms (root)two-component system, OmpR family, response regulator,two-component system, OmpR family, phosphate regulon response regulator PhoB,two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
COG0745Bacteria (superkingdom)two-component system, OmpR family, response regulator,two-component system, OmpR family, phosphate regulon response regulator PhoB,two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
6AVYEActinobacteria (phylum)two-component system, OmpR family, response regulator,two-component system, OmpR family, response regulator RegX3,two-component system, OmpR family, response regulator MtrA
FA0Q9Actinomycetia (class)two-component system, OmpR family, response regulator,two-component system, OmpR family, response regulator RegX3,two-component system, OmpR family, response regulator MtrA
EN2JACorynebacteriales (order)two-component system, OmpR family, response regulator,two-component system, OmpR family, response regulator MprA,two-component system, OmpR family, response regulator RegX3
58XQAMycobacteriaceae (family)two-component system, OmpR family, response regulator MprA
HMXH5Mycobacterium (genus)two-component system, OmpR family, response regulator MprA
EK92GMycobacterium tuberculosis (species)two-component system, OmpR family, response regulator MprA

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: