Domains within Mycobacterium vanbaalenii PYR-1 protein A1T6F1_MYCVP (A1T6F1)

PAS/PAC sensor hybrid histidine kinase

Alternative representations: 1 /

Protein length1385 aa
Source databaseUniProt
Identifiers A1T6F1_MYCVP, A1T6F1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

A1T6F1_MYCVP is shown as Mvan_1931 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Mvan_1931

Protein A1T6F1_MYCVP is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system
map02025Biofilm formation - Pseudomonas aeruginosa

KEGG orthologous groups

KONameDescription
K02484K02484two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
K03406mcpmethyl-accepting chemotaxis protein
K07315rsbU_Pphosphoserine phosphatase RsbU/P [EC:3.1.3.3]
K02483K02483two-component system, OmpR family, response regulator
K04757rsbWserine/threonine-protein kinase RsbW [EC:2.7.11.1]
K21023mucRdiguanylate cyclase [EC:2.7.7.65]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 350058.Mvan_1931 in eggNOG.

OGTaxonomic classDescription
LCOG0642All organisms (root)two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3]
LCOG2172All organisms (root)serine/threonine-protein kinase RsbW [EC:2.7.11.1],serine/threonine-protein kinase RsbT [EC:2.7.11.1],stage II sporulation protein AB (anti-sigma F factor) [EC:2.7.11.1]
LCOG0745All organisms (root)two-component system, OmpR family, response regulator,two-component system, OmpR family, phosphate regulon response regulator PhoB,two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
LCOG2208All organisms (root)phosphoserine phosphatase RsbU/P [EC:3.1.3.3],two-component system, HptB-dependent secretion and biofilm response regulator,phosphoserine phosphatase RsbX [EC:3.1.3.3]
LCOG2202All organisms (root)methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],aerotaxis receptor
COG2202Bacteria (superkingdom)methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],aerotaxis receptor
COG0745Bacteria (superkingdom)two-component system, OmpR family, response regulator,two-component system, OmpR family, phosphate regulon response regulator PhoB,two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
COG0642Bacteria (superkingdom)two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3]
COG2208Bacteria (superkingdom)phosphoserine phosphatase RsbU/P [EC:3.1.3.3],two-component system, HptB-dependent secretion and biofilm response regulator,phosphoserine phosphatase RsbX [EC:3.1.3.3]
COG2172Bacteria (superkingdom)serine/threonine-protein kinase RsbW [EC:2.7.11.1],serine/threonine-protein kinase RsbT [EC:2.7.11.1],stage II sporulation protein AB (anti-sigma F factor) [EC:2.7.11.1]
69W9VActinobacteria (phylum)serine/threonine-protein kinase RsbW [EC:2.7.11.1],diguanylate cyclase [EC:2.7.7.65]
FAUH5Actinomycetia (class)diguanylate cyclase [EC:2.7.7.65]
ENCTRCorynebacteriales (order)HATPase_c_2,SpoIIE,PAS_4
58BE9Mycobacteriaceae (family)SpoIIE,HATPase_c_2,PAS_4
DY7AMMycolicibacterium (genus)PAS_4,SpoIIE,HisKA

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: