Domains within Mycobacterium vanbaalenii PYR-1 protein A1T6S5_MYCVP (A1T6S5)

Metal dependent phosphohydrolase

Alternative representations: 1 /

Protein length521 aa
Source databaseUniProt
Identifiers A1T6S5_MYCVP, A1T6S5

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Mesorhizobium loti

Predicted functional partners

A1T6S5_MYCVP is shown as Mvan_2058 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Mvan_2058

Protein A1T6S5_MYCVP is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system

KEGG orthologous groups

KONameDescription
K25135K25135cyclic di-GMP phosphodiesterase [EC:3.1.4.-]
K07693desRtwo-component system, NarL family, response regulator DesR
K07689uvrY, gacA, varAtwo-component system, NarL family, invasion response regulator UvrY

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 350058.Mvan_2058 in eggNOG.

OGTaxonomic classDescription
LCOG2197All organisms (root)two-component system, NarL family, invasion response regulator UvrY,two-component system, NarL family, nitrate/nitrite response regulator NarL,two-component system, NarL family, response regulator DesR
LCOG2206All organisms (root)cyclic di-GMP phosphodiesterase [EC:3.1.4.-],diguanylate cyclase [EC:2.7.7.65],methane/ammonia monooxygenase subunit B
COG2206Bacteria (superkingdom)cyclic di-GMP phosphodiesterase [EC:3.1.4.-],diguanylate cyclase [EC:2.7.7.65],methane/ammonia monooxygenase subunit B
COG2197Bacteria (superkingdom)two-component system, NarL family, invasion response regulator UvrY,two-component system, NarL family, nitrate/nitrite response regulator NarL,two-component system, NarL family, response regulator DesR
6AD0CActinobacteria (phylum)two-component system, NarL family, response regulator DesR,two-component system, NarL family, response regulator DevR,LuxR family transcriptional regulator, regulator of acetate metabolism
F9DU1Actinomycetia (class)HD_5,GerE,GGDEF
EN3XACorynebacteriales (order)HD_5,GerE
58ZMRMycobacteriaceae (family)HD_5,GerE
DY0GKMycolicibacterium (genus)HD_5,GerE

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: