Domains within Pan troglodytes protein TFP11_PANTR (A1XD93)

Tuftelin-interacting protein 11

Alternative representations: 1 /

Protein length837 aa
Source databaseUniProt
Identifiers TFP11_PANTR, A1XD93, ENSPTRP00000024442.5, ENSPTRP00000024442, K7B3F8_PANTR, K7B3F8
Source gene ENSPTRG00000014196

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

TFP11_PANTR is shown as TFIP11 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for TFIP11

Protein TFP11_PANTR is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04138Autophagy - yeast

KEGG orthologous groups

KONameDescription
K13103TFIP11tuftelin-interacting protein 11

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 26 PTMs annotated in this protein:

PTMCount
Phosphorylation16
Acetylation6
Ubiquitination4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein TFIP11.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9598.ENSPTRP00000024442 in eggNOG.

OGTaxonomic classDescription
LKOG2184All organisms (root)tuftelin-interacting protein 11,G patch domain-containing protein 2,autophagy-related protein 17
KOG2184Eukaryota (superkingdom)tuftelin-interacting protein 11,G patch domain-containing protein 2,autophagy-related protein 17
HSYVTMetazoa (kingdom)tuftelin-interacting protein 11,protein-tyrosine sulfotransferase [EC:2.8.2.20]
94VRWChordata (phylum)tuftelin-interacting protein 11,protein-tyrosine sulfotransferase [EC:2.8.2.20]
5QTP9Sarcopterygii (superclass)tuftelin-interacting protein 11,protein-tyrosine sulfotransferase [EC:2.8.2.20]
8Z96HMammalia (class)tuftelin-interacting protein 11
4RBMIEuarchontoglires (superorder)tuftelin-interacting protein 11
4ZSJ3Primates (order)tuftelin-interacting protein 11
98B5DHaplorrhini (suborder)tuftelin-interacting protein 11
BVBZXSimiiformes (infraorder)tuftelin-interacting protein 11
9EPXQCatarrhini (parvorder)tuftelin-interacting protein 11
H6FV5Bilateria (clade)tuftelin-interacting protein 11,protein-tyrosine sulfotransferase [EC:2.8.2.20]
7GMEVOpisthokonta (clade)tuftelin-interacting protein 11,autophagy-related protein 17,protein-tyrosine sulfotransferase [EC:2.8.2.20]
9FGZAVertebrata (clade)tuftelin-interacting protein 11,protein-tyrosine sulfotransferase [EC:2.8.2.20]
FX3YRHominoidea (superfamily)tuftelin-interacting protein 11
5N6EXHominidae (family)tuftelin-interacting protein 11
5Y95SHomininae (subfamily)tuftelin-interacting protein 11

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: