Domains within Prochlorococcus marinus str. MIT 9303 protein A2C5T3_PROM3 (A2C5T3)

ABC transporter, multi drug efflux family protein

Alternative representations: 1 /

Protein length975 aa
Source databaseUniProt
Identifiers A2C5T3_PROM3, A2C5T3

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Cyanobacteria

Predicted functional partners

A2C5T3_PROM3 is shown as ABM76843.1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ABM76843.1

Protein A2C5T3_PROM3 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system
map02010ABC transporters
map05133Pertussis

KEGG orthologous groups

KONameDescription
K11004hlyB, cyaBATP-binding cassette, subfamily B, bacterial HlyB/CyaB
K12541lapBATP-binding cassette, subfamily C, bacterial LapB
K10914crpCRP/FNR family transcriptional regulator, cyclic AMP receptor protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 59922.P9303_00861 in eggNOG.

OGTaxonomic classDescription
LCOG0664All organisms (root)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein,CRP/FNR family transcriptional regulator, anaerobic regulatory protein,cAMP-dependent protein kinase regulator
LCOG2274All organisms (root)ATP-binding cassette, subfamily C, bacterial LapB,ATP-binding cassette, subfamily B, bacterial HlyB/CyaB,ATP-binding cassette, subfamily B, bacterial
COG0664Bacteria (superkingdom)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein,CRP/FNR family transcriptional regulator, anaerobic regulatory protein,CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator
COG2274Bacteria (superkingdom)ATP-binding cassette, subfamily C, bacterial LapB,ATP-binding cassette, subfamily B, bacterial HlyB/CyaB,ATP-binding cassette, subfamily B, bacterial
HCC6HCyanobacteria (phylum)ATP-binding cassette, subfamily B, bacterial,ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
BEBYISynechococcales (order)ATP-binding cassette, subfamily B, bacterial,ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
HXDMIProchlorococcus (genus)ATP-binding cassette, subfamily B, bacterial,ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
8KQ7JProchlorococcus marinus (species)ATP-binding cassette, subfamily B, bacterial,ATP-binding cassette, subfamily B, bacterial HlyB/CyaB

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: