Domains within Maribacter sp. HTCC2170 protein A4AV00_MARSH (A4AV00)

DNA polymerase III, epsilon subunit

Alternative representations: 1 /

Protein length454 aa
Source databaseUniProt
Identifiers A4AV00_MARSH, A4AV00

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Mycobacterium tuberculosis complex

Predicted functional partners

A4AV00_MARSH is shown as EAR00403.1 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for EAR00403.1

Protein A4AV00_MARSH is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03430Mismatch repair
map03420Nucleotide excision repair
map03030DNA replication

KEGG orthologous groups

KONameDescription
K03703uvrCexcinuclease ABC subunit C
K02342dnaQDNA polymerase III subunit epsilon [EC:2.7.7.7] iPath3
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 313603.FB2170_13316 in eggNOG.

OGTaxonomic classDescription
LCOG0322All organisms (root)excinuclease ABC subunit C,DNA polymerase III subunit epsilon [EC:2.7.7.7],excinuclease Cho [EC:3.1.25.-]
LCOG2176All organisms (root)DNA polymerase III subunit epsilon [EC:2.7.7.7],DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7],ATP-dependent DNA helicase DinG [EC:5.6.2.3]
COG0322Bacteria (superkingdom)excinuclease ABC subunit C,DNA polymerase III subunit epsilon [EC:2.7.7.7],excinuclease Cho [EC:3.1.25.-]
COG2176Bacteria (superkingdom)DNA polymerase III subunit epsilon [EC:2.7.7.7],DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7],ATP-dependent DNA helicase DinG [EC:5.6.2.3]
G9YRCBacteroidetes (phylum)DNA polymerase III subunit epsilon [EC:2.7.7.7],excinuclease Cho [EC:3.1.25.-]
GDQKNFlavobacteriia (class)DNA polymerase III subunit epsilon [EC:2.7.7.7]
HJNG4Flavobacteriales (order)DNA polymerase III subunit epsilon [EC:2.7.7.7]
C1RU1Flavobacteriaceae (family)DNA polymerase III subunit epsilon [EC:2.7.7.7]
8I72DMaribacter (genus)DNA polymerase III subunit epsilon [EC:2.7.7.7]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: