Domains within Mycobacterium gilvum PYR-GCK protein A4TD81_MYCGI (A4TD81)
Putative GAF sensor protein
Alternative representations: 1 /
| Protein length | 851 aa |
|---|---|
| Source database | UniProt |
| Identifiers | A4TD81_MYCGI, A4TD81 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
A4TD81_MYCGI is shown as 
Mflv_4521 in the network
Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.
The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein A4TD81_MYCGI is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map02020 | Two-component system | |
| map02025 | Biofilm formation - Pseudomonas aeruginosa |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K02484 | K02484 | two-component system, OmpR family, sensor kinase [EC:2.7.13.3] | |
| K03406 | mcp | methyl-accepting chemotaxis protein | |
| K07315 | rsbU_P | phosphoserine phosphatase RsbU/P [EC:3.1.3.3] | |
| K02483 | K02483 | two-component system, OmpR family, response regulator | |
| K04757 | rsbW | serine/threonine-protein kinase RsbW [EC:2.7.11.1] | |
| K21023 | mucR | diguanylate cyclase [EC:2.7.7.65] |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 350054.Mflv_4521 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG2202 | All organisms (root) | methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],aerotaxis receptor |
| LCOG0642 | All organisms (root) | two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| LCOG2172 | All organisms (root) | serine/threonine-protein kinase RsbW [EC:2.7.11.1],serine/threonine-protein kinase RsbT [EC:2.7.11.1],stage II sporulation protein AB (anti-sigma F factor) [EC:2.7.11.1] |
| LCOG0745 | All organisms (root) | two-component system, OmpR family, response regulator,two-component system, OmpR family, phosphate regulon response regulator PhoB,two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP |
| LCOG2208 | All organisms (root) | phosphoserine phosphatase RsbU/P [EC:3.1.3.3],two-component system, HptB-dependent secretion and biofilm response regulator,phosphoserine phosphatase RsbX [EC:3.1.3.3] |
| COG0642 | Bacteria (superkingdom) | two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| COG0745 | Bacteria (superkingdom) | two-component system, OmpR family, response regulator,two-component system, OmpR family, phosphate regulon response regulator PhoB,two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP |
| COG2208 | Bacteria (superkingdom) | phosphoserine phosphatase RsbU/P [EC:3.1.3.3],two-component system, HptB-dependent secretion and biofilm response regulator,phosphoserine phosphatase RsbX [EC:3.1.3.3] |
| COG2202 | Bacteria (superkingdom) | methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],aerotaxis receptor |
| COG2172 | Bacteria (superkingdom) | serine/threonine-protein kinase RsbW [EC:2.7.11.1],serine/threonine-protein kinase RsbT [EC:2.7.11.1],stage II sporulation protein AB (anti-sigma F factor) [EC:2.7.11.1] |
| 68WH4 | Actinobacteria (phylum) | diguanylate cyclase [EC:2.7.7.65] |
| FAUH6 | Actinomycetia (class) | diguanylate cyclase [EC:2.7.7.65] |
| EMTX7 | Corynebacteriales (order) | GAF_2,HATPase_c_2,SpoIIE |
| 58BEC | Mycobacteriaceae (family) | GAF_2,SpoIIE,HATPase_c_2 |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.