Domains within Bos taurus protein NELL2_BOVIN (A6QR11)

Protein kinase C-binding protein NELL2

Alternative representations: 1 /

Protein length816 aa
Source databaseUniProt
Identifiers NELL2_BOVIN, A6QR11, ENSBTAP00000042993.3, ENSBTAP00000042993
Source gene ENSBTAG00000032183

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Tetrapoda

Predicted functional partners

NELL2_BOVIN is shown as NELL2 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for NELL2

Protein NELL2_BOVIN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05165Human papillomavirus infection

KEGG orthologous groups

KONameDescription
K00430E1.11.1.7peroxidase [EC:1.11.1.7] iPath3
K04659THBS2Sthrombospondin 2/3/4/5
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9913.ENSBTAP00000042993 in eggNOG.

OGTaxonomic classDescription
7553HAll organisms (root)peroxidase [EC:1.11.1.7],transmembrane channel-like protein,thrombospondin 2/3/4/5
KOG1217Eukaryota (superkingdom)peroxidase [EC:1.11.1.7],transmembrane channel-like protein,thrombospondin 2/3/4/5
HSY91Metazoa (kingdom)thrombospondin 2/3/4/5,delta,matrilin
93SQRChordata (phylum)protein kinase C-binding protein NELL
5QS16Sarcopterygii (superclass)protein kinase C-binding protein NELL
8YXGDMammalia (class)protein kinase C-binding protein NELL
BQWCKLaurasiatheria (superorder)protein kinase C-binding protein NELL
AXFWDArtiodactyla (order)protein kinase C-binding protein NELL
B5XTUPecora (infraorder)protein kinase C-binding protein NELL
9G5A4Vertebrata (clade)protein kinase C-binding protein NELL
H4QFHBilateria (clade)thrombospondin 2/3/4/5,delta,matrilin
7NXWDOpisthokonta (clade)thrombospondin 2/3/4/5,delta,matrilin
7PE7TBovidae (family)protein kinase C-binding protein NELL
DB7TSBovinae (subfamily)protein kinase C-binding protein NELL
AZH97Bos (genus)protein kinase C-binding protein NELL

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: