Domains within Mus musculus protein A8DIL0_MOUSE (A8DIL0)

Galectin

Alternative representations: 1 /

Protein length325 aa
Source databaseUniProt
Identifiers A8DIL0_MOUSE, A8DIL0, ENSMUSP00000114200.1, ENSMUSP00000114200
Source gene ENSMUSG00000057554
Alternative splicing LEG8_MOUSE, Q8C6H0_MOUSE, A8DIL0_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

A8DIL0_MOUSE is shown as Lgals8 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Lgals8

Protein A8DIL0_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04064NF-kappa B signaling pathway
map05131Shigellosis

KEGG orthologous groups

KONameDescription
K06832LGALS8galectin-8
K06830LGALS1galectin-1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000114200 in eggNOG.

OGTaxonomic classDescription
LKOG3587All organisms (root)galectin-1,galectin-3,galectin-2
KOG3587Eukaryota (superkingdom)galectin-1,galectin-3,galectin-2
HT67ZMetazoa (kingdom)galectin-8,galectin-12,galectin-4
93MUQChordata (phylum)galectin-12,galectin-8,ectodysplasin-A receptor-associated adapter protein
5R9J9Sarcopterygii (superclass)galectin-12,galectin-8,ectodysplasin-A receptor-associated adapter protein
8ZMX2Mammalia (class)galectin-12,galectin-8
4R8QKEuarchontoglires (superorder)galectin-12,galectin-8
AI168Rodentia (order)galectin-12,galectin-8
8DME5Myomorpha (suborder)galectin-8
7HN2MOpisthokonta (clade)galectin-8,galectin-12,galectin-4
9G116Vertebrata (clade)galectin-12,galectin-8,ectodysplasin-A receptor-associated adapter protein
H403TBilateria (clade)galectin-8,galectin-12,galectin-4
CQ87GMuridae (family)galectin-8
ADZQQMurinae (subfamily)galectin-8
5PI6QMus (genus)galectin-8
HE677Mus (subgenus)galectin-8

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: