Domains within Homo sapiens protein ZN785_HUMAN (A8K8V0)

Zinc finger protein 785

Alternative representations: 1 /

Protein length405 aa
Source databaseUniProt
Identifiers ZN785_HUMAN, A8K8V0, ENSP00000378642.2, ENSP00000378642, O75701, Q8IW91, Q8WV14, Q96MN0, A0A024QZC7_HUMAN, A0A024QZC7
Source gene ENSG00000197162
Alternative splicing H3BR67_HUMAN, A8K8V0-2, ZN785_HUMAN, I3L119_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Amniota

Predicted functional partners

ZN785_HUMAN is shown as ZNF785 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ZNF785

Protein ZN785_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05168Herpes simplex virus 1 infection

KEGG orthologous groups

KONameDescription
K09228KRABKRAB domain-containing zinc finger protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 3 PTMs annotated in this protein:

PTMCount
Phosphorylation3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ZNF785.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000378642 in eggNOG.

OGTaxonomic classDescription
LKOG1721All organisms (root)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
KOG1721Eukaryota (superkingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
HUGX0Metazoa (kingdom)KRAB domain-containing zinc finger protein
93RG8Chordata (phylum)KRAB domain-containing zinc finger protein
5QD9DSarcopterygii (superclass)KRAB domain-containing zinc finger protein
8Z7X5Mammalia (class)KRAB domain-containing zinc finger protein
4RMZBEuarchontoglires (superorder)KRAB domain-containing zinc finger protein
4ZUGFPrimates (order)KRAB domain-containing zinc finger protein
98QP4Haplorrhini (suborder)KRAB domain-containing zinc finger protein
BV5VVSimiiformes (infraorder)KRAB domain-containing zinc finger protein
9EVCSCatarrhini (parvorder)KRAB domain-containing zinc finger protein
9GHAVVertebrata (clade)KRAB domain-containing zinc finger protein
H3TKRBilateria (clade)KRAB domain-containing zinc finger protein
7JY1SOpisthokonta (clade)KRAB domain-containing zinc finger protein
FX29WHominoidea (superfamily)KRAB domain-containing zinc finger protein
5MX64Hominidae (family)KRAB domain-containing zinc finger protein
5Y3ZJHomininae (subfamily)KRAB domain-containing zinc finger protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: