Domains within Caenorhabditis briggsae protein KPC3_CAEBR (A8WUG4)

Protein kinase C-like 3

Alternative representations: 1 /

Protein length597 aa
Source databaseUniProt
Identifiers H6UEN0_9PELO, H6UEN0, KPC3_CAEBR, A8WUG4

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

KPC3_CAEBR is shown as pkc-3 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for pkc-3

Protein KPC3_CAEBR is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04360Axon guidance
map04015Rap1 signaling pathway

KEGG orthologous groups

KONameDescription
K08852ERN1serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K06069PRKCIatypical protein kinase C iota type [EC:2.7.11.13]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 6238.A8WUG4 in eggNOG.

OGTaxonomic classDescription
LCOG0478All organisms (root)serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-],RAC serine/threonine-protein kinase [EC:2.7.11.1],pto-interacting protein 1 [EC:2.7.11.1]
KOG0695Eukaryota (superkingdom)atypical protein kinase C iota type [EC:2.7.11.13],atypical protein kinase C zeta type [EC:2.7.11.13],gamma-aminobutyric acid receptor subunit delta
HUN0BMetazoa (kingdom)atypical protein kinase C iota type [EC:2.7.11.13],atypical protein kinase C zeta type [EC:2.7.11.13],protein phosphatase 1 regulatory subunit 14C
8BFYCNematoda (phylum)atypical protein kinase C iota type [EC:2.7.11.13]
HDHQUChromadorea (class)atypical protein kinase C iota type [EC:2.7.11.13]
6DPD4Rhabditida (order)atypical protein kinase C iota type [EC:2.7.11.13]
8PI70Rhabditina (suborder)atypical protein kinase C iota type [EC:2.7.11.13]
7HT82Opisthokonta (clade)atypical protein kinase C iota type [EC:2.7.11.13],atypical protein kinase C zeta type [EC:2.7.11.13],protein phosphatase 1 regulatory subunit 14C
H5S8CBilateria (clade)atypical protein kinase C iota type [EC:2.7.11.13],atypical protein kinase C zeta type [EC:2.7.11.13],protein phosphatase 1 regulatory subunit 14C
AYPYMRhabditidae (family)atypical protein kinase C iota type [EC:2.7.11.13]
BTGWRCaenorhabditis (genus)atypical protein kinase C iota type [EC:2.7.11.13]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: