Domains within Culex quinquefasciatus protein B0WVX3_CULQU (B0WVX3)

ATP-dependent RNA helicase DHX8

Alternative representations: 1 /

Protein length1253 aa
Source databaseUniProt
Identifiers B0WVX3_CULQU, B0WVX3

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

B0WVX3_CULQU is shown as B0WVX3_CULQU in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for B0WVX3_CULQU

Protein B0WVX3_CULQU is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03040Spliceosome

KEGG orthologous groups

KONameDescription
K03578hrpAATP-dependent RNA helicase HrpA [EC:5.6.2.6]
K12818DHX8, PRP22ATP-dependent RNA helicase DHX8/PRP22 [EC:5.6.2.6]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7176.B0WVX3 in eggNOG.

OGTaxonomic classDescription
LCOG1643All organisms (root)ATP-dependent helicase HrpA [EC:3.6.4.13],ATP-dependent helicase HrpB [EC:3.6.4.13],ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
EJG9ZEndopterygota (cohort)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
KOG0922Eukaryota (superkingdom)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13],ATP-dependent RNA helicase DDX35 [EC:3.6.4.13],transcription factor TGA
HUFV3Metazoa (kingdom)ATP-dependent RNA helicase DDX35 [EC:3.6.4.13],ATP-dependent RNA helicase DHX34 [EC:3.6.4.13],ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
HIEERArthropoda (phylum)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
85FTRHexapoda (subphylum)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
AHQUKNeoptera (infraclass)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
AP00JDiptera (order)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
G9MFYCulicomorpha (infraorder)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
H6F06Bilateria (clade)ATP-dependent RNA helicase DDX35 [EC:3.6.4.13],ATP-dependent RNA helicase DHX34 [EC:3.6.4.13],ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
7HUJVOpisthokonta (clade)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13],ATP-dependent RNA helicase DDX35 [EC:3.6.4.13],ATP-dependent RNA helicase DHX33 [EC:3.6.4.13]
9M25BCulicidae (family)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]
DAAU4Culicinae (subfamily)ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: