Domains within Proteus mirabilis protein A0A1Z1SXD4_PROMI (A0A1Z1SXD4)
2-oxoglutarate dehydrogenase subunit E1
Alternative representations: 1 /
| Protein length | 934 aa |
|---|---|
| Source database | UniProt |
| Identifiers | B4ESQ9_PROMH, B4ESQ9, A0A1F2K8M9_9GAMM, A0A1F2K8M9, A0A1Z1SXD4_PROMI, A0A1Z1SXD4 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
A0A1Z1SXD4_PROMI is shown as 
sucA in the network
Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.
The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein A0A1Z1SXD4_PROMI is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map00020 | Citrate cycle (TCA cycle) | iPath3 |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K00164 | OGDH, sucA | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] | iPath3 |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 584.AOUC001_12965 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG0567 | All organisms (root) | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2],multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61],probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 [EC:1.2.4.2] |
| COG0567 | Bacteria (superkingdom) | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2],multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61],putative transcriptional regulator |
| 5YWRC | Proteobacteria (phylum) | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] |
| EQV81 | Gammaproteobacteria (class) | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] |
| AUDX7 | Enterobacterales (order) | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] |
| 67M9E | Morganellaceae (family) | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] |
| ACBXY | Proteus (genus) | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.