Domains within Drosophila persimilis protein B4GTC4_DROPE (B4GTC4)

Phosphoinositide phospholipase C

Alternative representations: 1 /

Protein length924 aa
Source databaseUniProt
Identifiers B4GTC4_DROPE, B4GTC4

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

B4GTC4_DROPE is shown as DperGL14297 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for DperGL14297

Protein B4GTC4_DROPE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04924Renin secretion

KEGG orthologous groups

KONameDescription
K05857PLCDphosphatidylinositol phospholipase C, delta [EC:3.1.4.11] iPath3
K05858PLCBphosphatidylinositol phospholipase C, beta [EC:3.1.4.11] iPath3
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7234.B4GTC4 in eggNOG.

OGTaxonomic classDescription
64TK7obscura group (species group)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
LKOG0169All organisms (root)phosphatidylinositol phospholipase C, delta [EC:3.1.4.11],inactive phospholipase C-like protein 2,phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]
EJGRVEndopterygota (cohort)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
KOG0169Eukaryota (superkingdom)phosphatidylinositol phospholipase C, delta [EC:3.1.4.11],inactive phospholipase C-like protein 2,phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]
HV33XMetazoa (kingdom)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
HI9Q2Arthropoda (phylum)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
86DREHexapoda (subphylum)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
AH8ICNeoptera (infraclass)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
ANYF3Diptera (order)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
H3PPFBilateria (clade)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
7H74ROpisthokonta (clade)phosphatidylinositol phospholipase C, delta [EC:3.1.4.11],inactive phospholipase C-like protein 2,phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]
EGTR5Drosophila (genus)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
50BIDSophophora (subgenus)phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: