Domains within Ixodes scapularis protein B7PCI4_IXOSC (B7PCI4)

RING-type E3 ubiquitin transferase

Alternative representations: 1 /

Protein length362 aa
Source databaseUniProt
Identifiers B7PCI4_IXOSC, B7PCI4

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

B7PCI4_IXOSC is shown as B7PCI4_IXOSC in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for B7PCI4_IXOSC

Protein B7PCI4_IXOSC is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04621NOD-like receptor signaling pathway

KEGG orthologous groups

KONameDescription
K11968ARIH1ariadne-1 [EC:2.3.2.31]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 6945.B7PCI4 in eggNOG.

OGTaxonomic classDescription
LKOG1815All organisms (root)ariadne-1 [EC:2.3.2.31],E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31],E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
KOG1815Eukaryota (superkingdom)ariadne-1 [EC:2.3.2.31],E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31],E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
HW0QZMetazoa (kingdom)E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31],transmembrane 9 superfamily member 2/4
HIB7SArthropoda (phylum)E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
G3MSYArachnida (class)E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
B6TM1Acari (subclass)E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
H4DDCBilateria (clade)E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31],transmembrane 9 superfamily member 2/4
7IEZIOpisthokonta (clade)E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31],transmembrane 9 superfamily member 2/4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: