Domains within Cyanothece sp. PCC 7425 protein B8HUG4_CYAP4 (B8HUG4)

Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)

Alternative representations: 1 /

Protein length583 aa
Source databaseUniProt
Identifiers B8HUG4_CYAP4, B8HUG4

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

B8HUG4_CYAP4 is shown as ACL46166.1 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ACL46166.1

Protein B8HUG4_CYAP4 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system
map02025Biofilm formation - Pseudomonas aeruginosa
map02026Biofilm formation - Escherichia coli

KEGG orthologous groups

KONameDescription
K13590dgcBdiguanylate cyclase [EC:2.7.7.65]
K02482flgStwo-component system, NtrC family, sensor kinase [EC:2.7.13.3]
K03406mcpmethyl-accepting chemotaxis protein
K21023mucRdiguanylate cyclase [EC:2.7.7.65]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 395961.Cyan7425_3848 in eggNOG.

OGTaxonomic classDescription
LCOG2202All organisms (root)methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],aerotaxis receptor
LCOG2200All organisms (root)diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],RNase E specificity factor CsrD
LCOG3322All organisms (root)methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],adenylate cyclase [EC:4.6.1.1]
LCOG2199All organisms (root)diguanylate cyclase [EC:2.7.7.65],two-component system, cell cycle response regulator [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52]
COG3322Bacteria (superkingdom)methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],adenylate cyclase [EC:4.6.1.1]
COG2200Bacteria (superkingdom)diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],RNase E specificity factor CsrD
COG2202Bacteria (superkingdom)methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],aerotaxis receptor
COG2199Bacteria (superkingdom)diguanylate cyclase [EC:2.7.7.65],two-component system, cell cycle response regulator [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52]
HCE9TCyanobacteria (phylum)diguanylate cyclase [EC:2.7.7.65],two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
AS2EROscillatoriophycideae (subclass)EAL,GGDEF,PAS_9
A8VQ5Oscillatoriales (order)EAL,GGDEF,PAS_9

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: