Domains within Jonesia denitrificans DSM 20603 protein C7QZF1_JONDD (C7QZF1)
2-oxoglutarate dehydrogenase, E1 subunit
Alternative representations: 1 /
| Protein length | 1258 aa |
|---|---|
| Source database | UniProt |
| Identifiers | C7QZF1_JONDD, C7QZF1 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
C7QZF1_JONDD is shown as 
Jden_1806 in the network
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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein C7QZF1_JONDD is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map00020 | Citrate cycle (TCA cycle) | iPath3 |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K00627 | DLAT, aceF, pdhC | pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] | iPath3 |
| K01616 | kgd | multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61] | |
| K00164 | OGDH, sucA | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] | iPath3 |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 471856.Jden_1806 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG0567 | All organisms (root) | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2],multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61],probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 [EC:1.2.4.2] |
| LCOG0508 | All organisms (root) | pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12],2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61],2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] |
| COG0567 | Bacteria (superkingdom) | 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2],multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61],putative transcriptional regulator |
| COG0508 | Bacteria (superkingdom) | pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12],2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61],2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] |
| 69WIV | Actinobacteria (phylum) | multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61],2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] |
| FAT7E | Actinomycetia (class) | multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61],2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] |
| EVSRS | Micrococcales (order) | multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61],2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.