Domains within Homo sapiens protein TIM14_HUMAN (Q96DA6)

Mitochondrial import inner membrane translocase subunit TIM14

Alternative representations: 1 /

Protein length116 aa
Source databaseUniProt
Identifiers TIM14_HUMAN, Q96DA6, ENSP00000372005.2, ENSP00000372005, B2R4B1, C9JBV1, TIM14_PONAB, Q5RF34, A0A0S2Z5X1_HUMAN, A0A0S2Z5X1, F7H8X3_MACMU, F7H8X3, H2R7X0_PANTR, H2R7X0, G3R157_GORGO, G3R157, A0A2K5TNF4_MACFA, A0A2K5TNF4, A0A2J8WGW3_PONAB, A0A2J8WGW3, G1T6M1_RABIT, G1T6M1, A0A0D9RL68_CHLSB, A0A0D9RL68, A0A2K6MGZ1_RHIBE, A0A2K6MGZ1, A0A2K6CUY6_MACNE, A0A2K6CUY6, A0A2K5MF86_CERAT, A0A2K5MF86, M3WDJ7_FELCA, M3WDJ7, A0A2I3MU57_PAPAN, A0A2I3MU57, A0A2K5CTB3_AOTNA, A0A2K5CTB3, A0A2K6G4V1_PROCO, A0A2K6G4V1, A0A2K5K6H2_COLAP, A0A2K5K6H2, A0A2K5ZZ40_MANLE, A0A2K5ZZ40, A0A0P6K6F2_HETGA, A0A0P6K6F2, A0A2J8L6X2_PANTR, A0A2J8L6X2, A0A2J8WGZ8_PONAB, A0A2J8WGZ8, A0A2K6MGZ3_RHIBE, A0A2K6MGZ3, A0A2K6PSQ5_RHIRO, A0A2K6PSQ5, A0A2K5K6H0_COLAP, A0A2K5K6H0, A0A2K5ZZ75_MANLE, A0A2K5ZZ75, Q96DA6-2, G3HTK1_CRIGR, G3HTK1
Source gene ENSG00000205981
Alternative splicing TIM14_HUMAN, G5E9V2_HUMAN, F2Z3A7_HUMAN, ENSP00000420767.1, ENSP00000496456.1, ENSP00000496401.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

TIM14_HUMAN is shown as DNAJC19 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for DNAJC19

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 5 PTMs annotated in this protein:

PTMCount
Ubiquitination2
Acetylation2
Phosphorylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein DNAJC19.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000372005 in eggNOG.

OGTaxonomic classDescription
LKOG0723All organisms (root)DnaJ homolog subfamily C member 19,DnaJ homolog subfamily C member 15
KOG0723Eukaryota (superkingdom)DnaJ homolog subfamily C member 19,DnaJ homolog subfamily C member 15
HTKN4Metazoa (kingdom)DnaJ homolog subfamily C member 19,DnaJ homolog subfamily C member 15
93Z92Chordata (phylum)DnaJ homolog subfamily C member 19,DnaJ homolog subfamily C member 15
5R0MTSarcopterygii (superclass)DnaJ homolog subfamily C member 19
8YVJVMammalia (class)DnaJ homolog subfamily C member 19
4RJ9MEuarchontoglires (superorder)DnaJ homolog subfamily C member 19
4ZQMFPrimates (order)DnaJ homolog subfamily C member 19
98AJDHaplorrhini (suborder)DnaJ homolog subfamily C member 19
BV9HBSimiiformes (infraorder)DnaJ homolog subfamily C member 19
9F0E5Catarrhini (parvorder)DnaJ homolog subfamily C member 19
9GT5HVertebrata (clade)DnaJ homolog subfamily C member 19,DnaJ homolog subfamily C member 15
H3C75Bilateria (clade)DnaJ homolog subfamily C member 19,DnaJ homolog subfamily C member 15
7NBTYOpisthokonta (clade)DnaJ homolog subfamily C member 19,DnaJ homolog subfamily C member 15
FX55UHominoidea (superfamily)DnaJ homolog subfamily C member 19
5N0DVHominidae (family)DnaJ homolog subfamily C member 19
5XYC1Homininae (subfamily)DnaJ homolog subfamily C member 19

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: