Domains within Homo sapiens protein KBTBD_HUMAN (C9JR72)

Kelch repeat and BTB domain-containing protein 13

Alternative representations: 1 /

Protein length458 aa
Source databaseUniProt
Identifiers KBTBD_HUMAN, C9JR72, ENSP00000388723.2, ENSP00000388723
Source gene ENSG00000234438

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

KBTBD_HUMAN is shown as KBTBD13 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for KBTBD13

Protein KBTBD_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04120Ubiquitin mediated proteolysis

KEGG orthologous groups

KONameDescription
K10449KLHL11kelch-like protein 11

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000388723 in eggNOG.

OGTaxonomic classDescription
LKOG1072All organisms (root)kelch-like protein 11,kelch repeat and BTB domain-containing protein 13,kelch-like protein 33
KOG1072Eukaryota (superkingdom)kelch-like protein 11,kelch repeat and BTB domain-containing protein 13,kelch-like protein 33
HVE64Metazoa (kingdom)kelch repeat and BTB domain-containing protein 13
94T75Chordata (phylum)kelch repeat and BTB domain-containing protein 13
5QJXJSarcopterygii (superclass)kelch repeat and BTB domain-containing protein 13
8Z2YAMammalia (class)kelch repeat and BTB domain-containing protein 13
4R4FPEuarchontoglires (superorder)kelch repeat and BTB domain-containing protein 13
505N5Primates (order)kelch repeat and BTB domain-containing protein 13
98QTKHaplorrhini (suborder)kelch repeat and BTB domain-containing protein 13
BV914Simiiformes (infraorder)kelch repeat and BTB domain-containing protein 13
9EXF9Catarrhini (parvorder)kelch repeat and BTB domain-containing protein 13
7JN11Opisthokonta (clade)kelch repeat and BTB domain-containing protein 13
9GUB8Vertebrata (clade)kelch repeat and BTB domain-containing protein 13
H3ZDKBilateria (clade)kelch repeat and BTB domain-containing protein 13
FWXQAHominoidea (superfamily)kelch repeat and BTB domain-containing protein 13
5N20PHominidae (family)kelch repeat and BTB domain-containing protein 13
5XTQFHomininae (subfamily)kelch repeat and BTB domain-containing protein 13

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: