Domains within Rattus norvegicus protein D3ZHH8_RAT (D3ZHH8)

Serum response factor

Alternative representations: 1 /

Protein length504 aa
Source databaseUniProt
Identifiers D3ZHH8_RAT, D3ZHH8, ENSRNOP00000058149.3, ENSRNOP00000058149
Source gene ENSRNOG00000018232

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

D3ZHH8_RAT is shown as Srf in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Srf

Protein D3ZHH8_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05203Viral carcinogenesis

KEGG orthologous groups

KONameDescription
K04378SRFserum response factor

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000058149 in eggNOG.

OGTaxonomic classDescription
LKOG0015All organisms (root)serum response factor,pheromone receptor transcription factor,arginine metabolism regulation protein I
KOG0015Eukaryota (superkingdom)serum response factor,pheromone receptor transcription factor,arginine metabolism regulation protein I
HUF78Metazoa (kingdom)serum response factor,pheromone receptor transcription factor
93NNJChordata (phylum)serum response factor
5QRQ5Sarcopterygii (superclass)serum response factor
8ZKQ3Mammalia (class)serum response factor
4R4NFEuarchontoglires (superorder)serum response factor
AIBKERodentia (order)serum response factor
8DE3JMyomorpha (suborder)serum response factor
H5DRNBilateria (clade)serum response factor,pheromone receptor transcription factor
7JRG4Opisthokonta (clade)serum response factor,pheromone receptor transcription factor,arginine metabolism regulation protein I
9FQZQVertebrata (clade)serum response factor
CQ16FMuridae (family)serum response factor
AE7SGMurinae (subfamily)serum response factor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: