Domains within Rattus norvegicus protein D3ZTY5_RAT (D3ZTY5)

USH1 protein network component sans

Alternative representations: 1 /

Protein length461 aa
Source databaseUniProt
Identifiers D3ZTY5_RAT, D3ZTY5, ENSRNOP00000032135.2, ENSRNOP00000032135
Source gene ENSRNOG00000028456

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

D3ZTY5_RAT is shown as Ush1g in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ush1g

Protein D3ZTY5_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05166Human T-cell leukemia virus 1 infection

KEGG orthologous groups

KONameDescription
K10999CESAcellulose synthase A [EC:2.4.1.12]
K06867K06867uncharacterized protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation2
Acetylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSRNOG00000028456.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000032135 in eggNOG.

OGTaxonomic classDescription
LCOG0666All organisms (root)uncharacterized protein,Mce-associated membrane protein,cellulose synthase A [EC:2.4.1.12]
KOG0504Eukaryota (superkingdom)cellulose synthase A [EC:2.4.1.12],beta-mannan synthase [EC:2.4.1.32],uncharacterized protein
HV7Q2Metazoa (kingdom)ankyrin repeat and SAM domain-containing protein 4B,Usher syndrome type-1G protein
93YYRChordata (phylum)ankyrin repeat and SAM domain-containing protein 4B,Usher syndrome type-1G protein
5R2GASarcopterygii (superclass)Usher syndrome type-1G protein
8YZQ4Mammalia (class)Usher syndrome type-1G protein
4R5R2Euarchontoglires (superorder)Usher syndrome type-1G protein
AHZYVRodentia (order)Usher syndrome type-1G protein
8DC5IMyomorpha (suborder)Usher syndrome type-1G protein
7HPSDOpisthokonta (clade)ankyrin repeat and SAM domain-containing protein 4B,Usher syndrome type-1G protein
9FIRUVertebrata (clade)ankyrin repeat and SAM domain-containing protein 4B,Usher syndrome type-1G protein
H395SBilateria (clade)ankyrin repeat and SAM domain-containing protein 4B,Usher syndrome type-1G protein
CQBHCMuridae (family)Usher syndrome type-1G protein
AEA2KMurinae (subfamily)Usher syndrome type-1G protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: