Domains within Thermus scotoductus SA-01 protein E8PN10_THESS (E8PN10)
DNA polymerase III, subunit epsilon
Alternative representations: 1 /
| Protein length | 637 aa |
|---|---|
| Source database | UniProt |
| Identifiers | W2U5L1_9DEIN, W2U5L1, E8PN10_THESS, E8PN10 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
E8PN10_THESS is shown as 
ADW21361.1 in the network
Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.
The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein E8PN10_THESS is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map02020 | Two-component system | |
| map03430 | Mismatch repair | |
| map03030 | DNA replication |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K07636 | phoR | two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] | |
| K02342 | dnaQ | DNA polymerase III subunit epsilon [EC:2.7.7.7] | iPath3 |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 743525.TSC_c07340 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG2176 | All organisms (root) | DNA polymerase III subunit epsilon [EC:2.7.7.7],DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7],ATP-dependent DNA helicase DinG [EC:5.6.2.3] |
| LCOG5002 | All organisms (root) | two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3],two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3],two-component system, OmpR family, sensor kinase [EC:2.7.13.3] |
| COG2176 | Bacteria (superkingdom) | DNA polymerase III subunit epsilon [EC:2.7.7.7],DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7],ATP-dependent DNA helicase DinG [EC:5.6.2.3] |
| COG5002 | Bacteria (superkingdom) | two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3],two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3],two-component system, OmpR family, sensor kinase [EC:2.7.13.3] |
| 7Q1Y8 | Deinococci (class) | DNA polymerase III subunit epsilon [EC:2.7.7.7] |
| DSN64 | Thermaceae (family) | DNA polymerase III subunit epsilon [EC:2.7.7.7] |
| 64V4B | Thermus (genus) | DNA polymerase III subunit epsilon [EC:2.7.7.7] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.