Domains within Mus musculus protein MPIP1_MOUSE (P48964)

M-phase inducer phosphatase 1

Alternative representations: 1 /

Protein length514 aa
Source databaseUniProt
Identifiers MPIP1_MOUSE, P48964, ENSMUSP00000091882.3, ENSMUSP00000091882, E9PVD0
Source gene ENSMUSG00000032477
Alternative splicing MPIP1_MOUSE, A0A0G2JEL7_MOUSE, Q3UQK4_MOUSE, A0A0G2JEF5_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

MPIP1_MOUSE is shown as Cdc25a in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Cdc25a

Protein MPIP1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04914Progesterone-mediated oocyte maturation

KEGG orthologous groups

KONameDescription
K23214AUTS2autism susceptibility gene 2 protein
K06645CDC25AM-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866CDC25BM-phase inducer phosphatase 2 [EC:3.1.3.48]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000091882 in eggNOG.

OGTaxonomic classDescription
LKOG3772All organisms (root)autism susceptibility gene 2 protein,M-phase inducer phosphatase 2 [EC:3.1.3.48],P2X purinoceptor 1
KOG3772Eukaryota (superkingdom)autism susceptibility gene 2 protein,M-phase inducer phosphatase 2 [EC:3.1.3.48],P2X purinoceptor 1
HTN0FMetazoa (kingdom)M-phase inducer phosphatase 2 [EC:3.1.3.48],M-phase inducer phosphatase 1 [EC:3.1.3.48],M-phase inducer phosphatase 3 [EC:3.1.3.48]
93US1Chordata (phylum)M-phase inducer phosphatase 2 [EC:3.1.3.48],M-phase inducer phosphatase 1 [EC:3.1.3.48],M-phase inducer phosphatase 3 [EC:3.1.3.48]
5QF7ASarcopterygii (superclass)M-phase inducer phosphatase 1 [EC:3.1.3.48],M-phase inducer phosphatase 2 [EC:3.1.3.48],M-phase inducer phosphatase 3 [EC:3.1.3.48]
8ZNN0Mammalia (class)M-phase inducer phosphatase 3 [EC:3.1.3.48],M-phase inducer phosphatase 1 [EC:3.1.3.48]
4REVUEuarchontoglires (superorder)M-phase inducer phosphatase 1 [EC:3.1.3.48],M-phase inducer phosphatase 3 [EC:3.1.3.48]
AI0N0Rodentia (order)M-phase inducer phosphatase 1 [EC:3.1.3.48],M-phase inducer phosphatase 3 [EC:3.1.3.48]
8DI75Myomorpha (suborder)M-phase inducer phosphatase 1 [EC:3.1.3.48]
7JPKAOpisthokonta (clade)M-phase inducer phosphatase 2 [EC:3.1.3.48],M-phase inducer tyrosine phosphatase [EC:3.1.3.48],M-phase inducer phosphatase 1 [EC:3.1.3.48]
9FASFVertebrata (clade)M-phase inducer phosphatase 2 [EC:3.1.3.48],M-phase inducer phosphatase 1 [EC:3.1.3.48],M-phase inducer phosphatase 3 [EC:3.1.3.48]
H3ZEXBilateria (clade)M-phase inducer phosphatase 2 [EC:3.1.3.48],M-phase inducer phosphatase 1 [EC:3.1.3.48],M-phase inducer phosphatase 3 [EC:3.1.3.48]
CQ31GMuridae (family)M-phase inducer phosphatase 1 [EC:3.1.3.48]
ADY7CMurinae (subfamily)M-phase inducer phosphatase 1 [EC:3.1.3.48]
5PUVVMus (genus)M-phase inducer phosphatase 1 [EC:3.1.3.48]
HE1K8Mus (subgenus)M-phase inducer phosphatase 1 [EC:3.1.3.48]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: