Domains within Homo sapiens protein TBG1_HUMAN (P23258)

Tubulin gamma-1 chain

Alternative representations: 1 /

Protein length451 aa
Source databaseUniProt
Identifiers P23258, TBG1_HUMAN, ENSP00000251413.2, ENSP00000251413, Q53X79, Q9BW59, H2QD29_PANTR, H2QD29, G7NIM0_MACMU, G7NIM0, G3SAS7_GORGO, G3SAS7, H0X1H2_OTOGA, H0X1H2, A0A2K5W6B9_MACFA, A0A2K5W6B9, A0A2J8RF31_PONAB, A0A2J8RF31, A0A0D9S1P2_CHLSB, A0A0D9S1P2, A0A2K6AP10_MACNE, A0A2K6AP10, A0A2K5LJL0_CERAT, A0A2K5LJL0, A0A2K6QS78_RHIRO, A0A2K6QS78, A0A096P5U1_PAPAN, A0A096P5U1, A0A2K6G337_PROCO, A0A2K6G337, A0A2K5Z0E6_MANLE, A0A2K5Z0E6
Source gene ENSG00000131462
Alternative splicing TBG1_HUMAN, ENSP00000464867.1, K7EKE5_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

TBG1_HUMAN is shown as TUBG1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for TUBG1

Protein TBG1_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05165Human papillomavirus infection

KEGG orthologous groups

KONameDescription
K10389TUBGtubulin gamma

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 36 PTMs annotated in this protein:

PTMCount
Ubiquitination20
Phosphorylation12
Acetylation4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein TUBG1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000251413 in eggNOG.

OGTaxonomic classDescription
LKOG1374All organisms (root)tubulin gamma,tubulin delta,tubulin beta
KOG1374Eukaryota (superkingdom)tubulin gamma,tubulin delta,tubulin beta
HTP7DMetazoa (kingdom)tubulin gamma
94WV3Chordata (phylum)tubulin gamma
5QKRRSarcopterygii (superclass)tubulin gamma
8YXYMMammalia (class)tubulin gamma
4RQGFEuarchontoglires (superorder)tubulin gamma
504TQPrimates (order)tubulin gamma
98QRGHaplorrhini (suborder)tubulin gamma
BVJ2CSimiiformes (infraorder)tubulin gamma
9ESFKCatarrhini (parvorder)tubulin gamma
7NHM0Opisthokonta (clade)tubulin gamma,aflatoxin B1 aldehyde reductase
9FJGRVertebrata (clade)tubulin gamma
H3SWRBilateria (clade)tubulin gamma
FWXJAHominoidea (superfamily)tubulin gamma
5NCNGHominidae (family)tubulin gamma
5XVEHHomininae (subfamily)tubulin gamma

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: